Allopregnanolone in the bed nucleus of the stria terminalis modulates contextual fear in rats
نویسندگان
چکیده
منابع مشابه
Allopregnanolone in the bed nucleus of the stria terminalis modulates contextual fear in rats
Trauma- and stress-related disorders are among the most common types of mental illness affecting the U.S. population. For many of these disorders, there is a striking sex difference in lifetime prevalence; for instance, women are twice as likely as men to be affected by posttraumatic stress disorder (PTSD). Gonadal steroids and their metabolites have been implicated in sex differences in fear a...
متن کاملThe bed nucleus of the stria terminalis mediates inter-individual variations in anxiety and fear.
While learning to fear stimuli that predict danger promotes survival, the inability to inhibit fear to inappropriate cues leads to a pernicious cycle of avoidance behaviors. Previous studies have revealed large inter-individual variations in fear responding with clinically anxious humans exhibiting a tendency to generalize learned fear to safe stimuli or situations. To shed light on the origin ...
متن کاملEffect of GABAA Receptors in the Rostral Ventrolateral Medulla on Cardiovascular Response to the Activation of the Bed Nucleus of the Stria Terminalis in Female Ovariectomized Rats
Background: The areas of the bed nucleus of the stria terminalis (BST) with a high density of estrogen receptors are involved in cardiovascular regulation and send axonal projections to the rostroventrolateral medulla (RVLM). We aimed to find the contribution of the RVLM to cardiovascular responses elicited by glutamate microinjection into the BST. Methods: Experiments were done in α-ch...
متن کاملRole of GABAA receptors of bed nucleus stria terminalis in controlling of blood pressure and heart rate in rats
Introduction: The Bed nucleus stria terminalis (BST) is a part of the limbic system. It was recently shown that chemical stimulation of the BST by L-glutamate elicited cardiovascular depressive responses. In the present study, we have investigated the possible cardiovascular role of the GABAergic receptors in BST by microinjection of its agonist and antagonists. Methods: Experiments were p...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Behavioral Neuroscience
سال: 2015
ISSN: 1662-5153
DOI: 10.3389/fnbeh.2015.00205